nuclear organization

Three-dimensional Chromatin Landscapes in T-Cell Acute Lymphoblastic Leukemia

On Epigenetic Plasticity and Genome Topology

The Dynamic 3D Chromatin Architecture Landscape of Acute Leukemia

Presenter: Aristotelis Tsirigos Other authors: Andreas Kloetgen, Palaniraja Thandapani, Panagiotis Ntziachristos, Charalampos Lazaris, Xufeng Chen, Hai Hu, Sofia Bakogianni, Jingjing Wang, Thomas Trimarchi, Yixing Zhu, Iannis Aifantis

3D Nuclear Organization

In this project, we explore genetic alterations of TAD boundaries in cancer and how they are potentially linked to oncogenic activity in T-ALL

Dynamic 3D chromosomal landscapes in acute leukemia

Presenter: Palaniraja Thandapani Other authors: Andreas Kloetgen, Charalampos Lazaris, Xufeng Chen, Panagiotis Ntziachristos, Aristotelis Tsirigos and Iannis Aifantis

Dynamic 3D Chromosomal Landscapes in T-ALL

Presenter: Andreas Kloetgen Other authors: Palaniraja Thandapani, Charalampos Lazaris, Panagiotis Ntziachristos, Aristotelis Tsirigos and Iannis Aifantis

Stratification of TAD Boundaries Reveals Preferential Insulation of Super Enhancers by Strong Boundaries

Low Grade Astrocytoma Mutations in IDH1, P53, and ATRX Cooperate to Block Differentiation of Human Neural Stem Cells via Repression of SOX2

Chromatin Organization Alterations in Critical Oncogenic Loci in Leukemia

Presenter: Aristotelis Tsirigos Other authors: Charalampos Lazaris, Panagiotis Ntziachristos, Nikolaos Kourtis, Stephen Kelly and Iannis Aifantis

HiC-bench: comprehensive and reproducible Hi-C data analysis designed for parameter exploration and benchmarking